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Evaluation of the antitumor mechanism of antibody‐drug conjugates against tissue factor in stroma‐rich allograft models

Tissue factor (TF) is known to be overexpressed in various cancers including pancreatic cancer. The upregulation of TF expression has been observed not only in tumor cells, but also in tumor stromal cells. Because of the potential of TF as a delivery target, several studies investigated the effectiv...

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Bibliografische gegevens
Gepubliceerd in:Cancer Sci
Hoofdauteurs: Tsumura, Ryo, Manabe, Shino, Takashima, Hiroki, Koga, Yoshikatsu, Yasunaga, Masahiro, Matsumura, Yasuhiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778651/
https://ncbi.nlm.nih.gov/pubmed/31348600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14146
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