ET-05 PRECLINICAL STUDY OF AN ANTI-HUMAN TISSUE FACTOR ANTIBODY-DRUG CONJUGATE IN A MALIGNANT GLIOMA XENOGRAFT MODEL

Whereas macromolecules such as antibody hardly extravasate from normal blood vessels compared with low molecular agents, macromolecules leak from tumor vasculature because of the enhanced permeability. As a result, macromolecules selectively accumulate at tumor sites. We apply this phenomenon, known...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neurooncol Adv
मुख्य लेखकों: Takashima, Hiroki, Manabe, Shino, Tsuji, Atsushi, Saga, Tsuneo, Tsumura, Ryo, Anzai, Takahiro, Koga, Yoshikatsu, Yasunaga, Masahiro, Kuroda, Jun-Ichiro, Mukasa, Akitake, Matsumura, Yasuhiro
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
Abstracts
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213193/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz039.039
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