Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models

For the creation of a successful antibody–drug conjugate (ADC), both scientific and clinical evidence has indicated that highly toxic anticancer agents (ACA) should be conjugated to a monoclonal antibody (mAb) to administer a reasonable amount of ADC to patients without compromising the affinity of...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yamamoto, Yoshiyuki, Hyodo, Ichinosuke, Koga, Yoshikatsu, Tsumura, Ryo, Sato, Ryuta, Obonai, Toshihumi, Fuchigami, Hirobumi, Furuya, Fumiaki, Yasunaga, Masahiro, Harada, Mitsunori, Kato, Yasuki, Ohtsu, Atsushi, Matsumura, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452165/
https://ncbi.nlm.nih.gov/pubmed/25711681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12645
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