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Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

BACKGROUND: Emphysema is a crucial pathological characteristic of chronic obstructive pulmonary disease (COPD). Oxidative stress, apoptosis and epigenetic mechanisms contribute to the pathogenesis of emphysema. However, an attempt to accurately identify whether these mechanisms interact with each ot...

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Podrobná bibliografie
Vydáno v:Respir Res
Hlavní autoři: Zeng, Huihui, Li, Tiao, He, Xue, Cai, Shan, Luo, Hong, Chen, Ping, Chen, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469342/
https://ncbi.nlm.nih.gov/pubmed/32883320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01495-w
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