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Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

BACKGROUND: Emphysema is a crucial pathological characteristic of chronic obstructive pulmonary disease (COPD). Oxidative stress, apoptosis and epigenetic mechanisms contribute to the pathogenesis of emphysema. However, an attempt to accurately identify whether these mechanisms interact with each ot...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Zeng, Huihui, Li, Tiao, He, Xue, Cai, Shan, Luo, Hong, Chen, Ping, Chen, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469342/
https://ncbi.nlm.nih.gov/pubmed/32883320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01495-w
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