The protective effect of PRMT6 overexpression on cigarette smoke extract-induced murine emphysema model

BACKGROUND: Cigarette smoke exposure is the most common risk factor for emphysema, which is one of the major pathologies of COPD. Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that specially catalyzes dimethylation of R2 in histone H3 (H3R2me2a). H3R2me2a prevents trimethylation o...

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Publicado en:Int J Chron Obstruct Pulmon Dis
Autores principales: He, Xue, Li, Tiao, Kang, Naixin, Zeng, Huihui, Ren, Siying, Zong, Dandan, Li, Jinhua, Cai, Shan, Chen, Ping, Chen, Yan
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680965/
https://ncbi.nlm.nih.gov/pubmed/29138553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S144881
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