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The protective effect of PRMT6 overexpression on cigarette smoke extract-induced murine emphysema model
BACKGROUND: Cigarette smoke exposure is the most common risk factor for emphysema, which is one of the major pathologies of COPD. Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that specially catalyzes dimethylation of R2 in histone H3 (H3R2me2a). H3R2me2a prevents trimethylation o...
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| Publicado en: | Int J Chron Obstruct Pulmon Dis |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove Medical Press
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680965/ https://ncbi.nlm.nih.gov/pubmed/29138553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S144881 |
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