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Oxidative stress mediates the apoptosis and epigenetic modification of the Bcl-2 promoter via DNMT1 in a cigarette smoke-induced emphysema model

BACKGROUND: Emphysema is a crucial pathological characteristic of chronic obstructive pulmonary disease (COPD). Oxidative stress, apoptosis and epigenetic mechanisms contribute to the pathogenesis of emphysema. However, an attempt to accurately identify whether these mechanisms interact with each ot...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Respir Res
Päätekijät: Zeng, Huihui, Li, Tiao, He, Xue, Cai, Shan, Luo, Hong, Chen, Ping, Chen, Yan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469342/
https://ncbi.nlm.nih.gov/pubmed/32883320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-01495-w
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