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Involvement of B-cell CLL/lymphoma 2 promoter methylation in cigarette smoke extract-induced emphysema

Abnormal apoptotic events play an important role in the pathogenesis of emphysema. The B-cell CLL/lymphoma 2 (Bcl-2) family proteins are essential and critical regulators of apoptosis. We determined whether the anti-apoptotic Bcl-2 play a role in the cigarette smoke extract (CSE)-induced emphysema....

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Zeng, Huihui, Shi, Zhihui, Kong, Xianglong, Chen, Yan, Zhang, Hongliang, Peng, Hong, Luo, Hong, Chen, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950400/
https://ncbi.nlm.nih.gov/pubmed/26924842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216635759
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