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C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities

Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules. They are difficult to synthesize chemically, but enzymatic synthesis production is a desirable pathway. Cyclic dipeptide prenyltransfera...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Liu, Rui, Zhang, Hongchi, Wu, Weiqiang, Li, Hui, An, Zhipeng, Zhou, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463755/
https://ncbi.nlm.nih.gov/pubmed/32806659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163676
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