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C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities

Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules. They are difficult to synthesize chemically, but enzymatic synthesis production is a desirable pathway. Cyclic dipeptide prenyltransfera...

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Publicat a:Molecules
Autors principals: Liu, Rui, Zhang, Hongchi, Wu, Weiqiang, Li, Hui, An, Zhipeng, Zhou, Feng
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463755/
https://ncbi.nlm.nih.gov/pubmed/32806659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163676
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