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The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

Ergot alkaloids are toxins and important pharmaceuticals that are produced biotechnologically on an industrial scale. The first committed step of ergot alkaloid biosynthesis is catalyzed by dimethylallyl tryptophan synthase (DMATS; EC 2.5.1.34). Orthologs of DMATS are found in many fungal genomes. W...

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Detalhes bibliográficos
Main Authors: Metzger, Ute, Schall, Christoph, Zocher, Georg, Unsöld, Inge, Stec, Edyta, Li, Shu-Ming, Heide, Lutz, Stehle, Thilo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732893/
https://ncbi.nlm.nih.gov/pubmed/19706516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904897106
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