The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

Ergot alkaloids are toxins and important pharmaceuticals that are produced biotechnologically on an industrial scale. The first committed step of ergot alkaloid biosynthesis is catalyzed by dimethylallyl tryptophan synthase (DMATS; EC 2.5.1.34). Orthologs of DMATS are found in many fungal genomes. W...

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Main Authors: Metzger, Ute, Schall, Christoph, Zocher, Georg, Unsöld, Inge, Stec, Edyta, Li, Shu-Ming, Heide, Lutz, Stehle, Thilo
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732893/
https://ncbi.nlm.nih.gov/pubmed/19706516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904897106
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