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C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities

Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules. They are difficult to synthesize chemically, but enzymatic synthesis production is a desirable pathway. Cyclic dipeptide prenyltransfera...

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Pubblicato in:Molecules
Autori principali: Liu, Rui, Zhang, Hongchi, Wu, Weiqiang, Li, Hui, An, Zhipeng, Zhou, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463755/
https://ncbi.nlm.nih.gov/pubmed/32806659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25163676
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