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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies

Gain-of-function mutations in human androgen receptor (AR) are among the major causes of drug resistance in prostate cancer (PCa). Identifying mutations that cause resistant phenotype is of critical importance for guiding treatment protocols, as well as for designing drugs that do not elicit adverse...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Snow, Oliver, Lallous, Nada, Ester, Martin, Cherkasov, Artem
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461580/
https://ncbi.nlm.nih.gov/pubmed/32823970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165847
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