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Deep Learning Modeling of Androgen Receptor Responses to Prostate Cancer Therapies

Gain-of-function mutations in human androgen receptor (AR) are among the major causes of drug resistance in prostate cancer (PCa). Identifying mutations that cause resistant phenotype is of critical importance for guiding treatment protocols, as well as for designing drugs that do not elicit adverse...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Snow, Oliver, Lallous, Nada, Ester, Martin, Cherkasov, Artem
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461580/
https://ncbi.nlm.nih.gov/pubmed/32823970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165847
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