How Do Molecular Dynamics Data Complement Static Structural Data of GPCRs

G protein-coupled receptors (GPCRs) are implicated in nearly every physiological process in the human body and therefore represent an important drug targeting class. Advances in X-ray crystallography and cryo-electron microscopy (cryo-EM) have provided multiple static structures of GPCRs in complex...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Torrens-Fontanals, Mariona, Stepniewski, Tomasz Maciej, Aranda-García, David, Morales-Pastor, Adrián, Medel-Lacruz, Brian, Selent, Jana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Review
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460635/
https://ncbi.nlm.nih.gov/pubmed/32824756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165933
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