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Dopamine D(2) Receptor Agonist Binding Kinetics—Role of a Conserved Serine Residue
The forward (k(on)) and reverse (k(off)) rate constants of drug–target interactions have important implications for therapeutic efficacy. Hence, time-resolved assays capable of measuring these binding rate constants may be informative to drug discovery efforts. Here, we used an ion channel activatio...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8071183/ https://ncbi.nlm.nih.gov/pubmed/33920848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22084078 |
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