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How and why do GPCRs dimerize?
Dimerization is fairly common in the G-protein-coupled receptor (GPCR) superfamily. First attempts to rationalize this phenomenon gave rise to an idea that two receptors in a dimer could be necessary to bind a single molecule of G protein or arrestin. Although GPCRs, G proteins and arrestins were cr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2652501/ https://ncbi.nlm.nih.gov/pubmed/18384890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2008.02.004 |
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