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GPCRs and signal transducers: interaction stoichiometry
Until the late 1990s class A G protein-coupled receptors (GPCRs) were believed to function as monomers. Then indirect evidence that they might internalize or even signal as dimers has emerged, along with proof that class C GPCRs are obligatory dimers. Crystal structures of GPCRs and their much large...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005764/ https://ncbi.nlm.nih.gov/pubmed/29739625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.04.002 |
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