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Stable retention of chloramphenicol-resistant mtDNA to rescue metabolically impaired cells

The permanent transfer of specific mtDNA sequences into mammalian cells could generate improved models of mtDNA disease and support future cell-based therapies. Previous studies documented multiple biochemical changes in recipient cells shortly after mtDNA transfer, but the long-term retention and f...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dawson, Emma R., Patananan, Alexander N., Sercel, Alexander J., Teitell, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7459123/
https://ncbi.nlm.nih.gov/pubmed/32868785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71199-0
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