RNA abasic sites in yeast and human cells

RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that, in yeast and human cells, RNA abasic sites are prevalent. When a base is lost from RNA, the remaining ribose is found as a closed-ring or a...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Liu, Yaojuan, Rodriguez, Yesenia, Ross, Robert L., Zhao, Ruoxia, Watts, Jason A., Grunseich, Christopher, Bruzel, Alan, Li, Dongjun, Burdick, Joshua T., Prasad, Rajendra, Crouch, Robert J., Limbach, Patrick A., Wilson, Samuel H., Cheung, Vivian G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456069/
https://ncbi.nlm.nih.gov/pubmed/32788345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011511117
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