RNA abasic sites in yeast and human cells

RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that, in yeast and human cells, RNA abasic sites are prevalent. When a base is lost from RNA, the remaining ribose is found as a closed-ring or a...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Liu, Yaojuan, Rodriguez, Yesenia, Ross, Robert L., Zhao, Ruoxia, Watts, Jason A., Grunseich, Christopher, Bruzel, Alan, Li, Dongjun, Burdick, Joshua T., Prasad, Rajendra, Crouch, Robert J., Limbach, Patrick A., Wilson, Samuel H., Cheung, Vivian G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2020
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456069/
https://ncbi.nlm.nih.gov/pubmed/32788345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011511117
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