RNA abasic sites in yeast and human cells

RNA abasic sites and the mechanisms involved in their regulation are mostly unknown; in contrast, DNA abasic sites are well-studied. We found surprisingly that, in yeast and human cells, RNA abasic sites are prevalent. When a base is lost from RNA, the remaining ribose is found as a closed-ring or a...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Liu, Yaojuan, Rodriguez, Yesenia, Ross, Robert L., Zhao, Ruoxia, Watts, Jason A., Grunseich, Christopher, Bruzel, Alan, Li, Dongjun, Burdick, Joshua T., Prasad, Rajendra, Crouch, Robert J., Limbach, Patrick A., Wilson, Samuel H., Cheung, Vivian G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456069/
https://ncbi.nlm.nih.gov/pubmed/32788345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011511117
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