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Mutational specificity and genetic control of replicative bypass of an abasic site in yeast

Abasic (AP) sites represent one of the most frequently formed lesions in DNA, and they present a strong block to continued synthesis by the replicative DNA polymerases (Pols). Here we determine the mutational specificity and the genetic control of translesion synthesis (TLS) opposite an AP site in y...

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Autori principali: Pagès, Vincent, Johnson, Robert E., Prakash, Louise, Prakash, Satya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234110/
https://ncbi.nlm.nih.gov/pubmed/18202176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711227105
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