Microdissected pancreatic cancer proteomes reveal tumor heterogeneity and therapeutic targets

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a relative paucity of cancer cells that are surrounded by an abundance of nontumor cells and extracellular matrix, known as stroma. The interaction between stroma and cancer cells contributes to poor outcome, but how proteins from these ind...

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Udgivet i:JCI Insight
Main Authors: Le Large, Tessa Y.S., Mantini, Giulia, Meijer, Laura L., Pham, Thang V., Funel, Niccola, van Grieken, Nicole C.T., Kok, Bart, Knol, Jaco, van Laarhoven, Hanneke W.M., Piersma, Sander R., Jimenez, Connie R., Kazemier, G., Giovannetti, Elisa, Bijlsma, Maarten F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455080/
https://ncbi.nlm.nih.gov/pubmed/32634123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138290
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