Microdissected pancreatic cancer proteomes reveal tumor heterogeneity and therapeutic targets

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a relative paucity of cancer cells that are surrounded by an abundance of nontumor cells and extracellular matrix, known as stroma. The interaction between stroma and cancer cells contributes to poor outcome, but how proteins from these ind...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Le Large, Tessa Y.S., Mantini, Giulia, Meijer, Laura L., Pham, Thang V., Funel, Niccola, van Grieken, Nicole C.T., Kok, Bart, Knol, Jaco, van Laarhoven, Hanneke W.M., Piersma, Sander R., Jimenez, Connie R., Kazemier, G., Giovannetti, Elisa, Bijlsma, Maarten F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455080/
https://ncbi.nlm.nih.gov/pubmed/32634123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.138290
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