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Efficient tin-mediated synthesis of lysophospholipid conjugates of a TLR7/8-active imidazoquinoline

The chemical synthesis of lysophospholipids often involves multiple synthetic and chromatographic steps due to the incorporation of the fatty acyl group onto the glycerol scaffold early in the synthesis. We report herein a new protocol for the lysophosphatidylation of alcohols and its application to...

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Publicado en:Tetrahedron Lett
Autores principales: Mwakwari, Sandra C., Bess, Laura S., Bazin, Hélène G., Johnson, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451898/
https://ncbi.nlm.nih.gov/pubmed/32863447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.03.110
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