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Phospholipidation of TLR7/8-active imidazoquinolines using a tandem phosphoramidite method
A high-yielding and scalable phosphoramidite procedure was developed for the phospholipidation of TLR7/8-active imidazoquinolines. This method involves the reaction of a 1,2-diacyl- or dialkyl-sn-glycerol or 3-chlolesterylalkanol with 2-cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite in the pre...
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| Vydáno v: | Tetrahedron Lett |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451945/ https://ncbi.nlm.nih.gov/pubmed/32863446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.03.091 |
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