Citrobacter rodentium Infection Inhibits Colonic P-glycoprotein Expression

P-glycoprotein (Pgp/MDR1) serves as a biological barrier that protects intestinal epithelial cells (IECs) by transporting out xenobiotics and bacterial toxins. Decreased Pgp function and expression has been seen in mouse models of inflammatory colitis and also in patients with IBD. Pgp knockout mice...

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Pubblicato in:Gene Rep
Autori principali: Patel, Mitul, Kumar, Anoop, Jayawardena, Dulari, Priyamvada, Shubha, Anbazhagan, Arivarasu N., Alrefai, Waddah A., Gill, Ravinder K., Dudeja, Pradeep K., Saksena, Seema
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451832/
https://ncbi.nlm.nih.gov/pubmed/32864506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genrep.2019.100549
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