Citrobacter rodentium Infection Inhibits Colonic P-glycoprotein Expression

P-glycoprotein (Pgp/MDR1) serves as a biological barrier that protects intestinal epithelial cells (IECs) by transporting out xenobiotics and bacterial toxins. Decreased Pgp function and expression has been seen in mouse models of inflammatory colitis and also in patients with IBD. Pgp knockout mice...

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Bibliografske podrobnosti
izdano v:Gene Rep
Main Authors: Patel, Mitul, Kumar, Anoop, Jayawardena, Dulari, Priyamvada, Shubha, Anbazhagan, Arivarasu N., Alrefai, Waddah A., Gill, Ravinder K., Dudeja, Pradeep K., Saksena, Seema
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7451832/
https://ncbi.nlm.nih.gov/pubmed/32864506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genrep.2019.100549
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