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Citrobacter rodentium Infection Inhibits Colonic P-glycoprotein Expression
P-glycoprotein (Pgp/MDR1) serves as a biological barrier that protects intestinal epithelial cells (IECs) by transporting out xenobiotics and bacterial toxins. Decreased Pgp function and expression has been seen in mouse models of inflammatory colitis and also in patients with IBD. Pgp knockout mice...
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| Опубликовано в: : | Gene Rep |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7451832/ https://ncbi.nlm.nih.gov/pubmed/32864506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genrep.2019.100549 |
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