Angiotensin II Inhibits P-glycoprotein in Intestinal Epithelial Cells

AIM: P-glycoprotein (P-gp/MDR1) plays a major role in intestinal homeostasis. Decrease in Pgp function and expression has been implicated in the pathogenesis of IBD. However, inhibitory mechanisms involved in the decrease of Pgp in inflammation are not fully understood. Angiotensin II (Ang II), a pe...

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Bibliographic Details
Published in:Acta Physiol (Oxf)
Main Authors: Kumar, Anoop, Priyamvada, Shubha, Soni, Vikas, Anbazhagan, Arivarasu N., Gujral, Tarunmeet, Gill, Ravinder K, Alrefai, Waddah A., Dudeja, Pradeep K., Saksena, Seema
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899205/
https://ncbi.nlm.nih.gov/pubmed/31177627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.13332
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