Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells

Intestinal P-glycoprotein (Pgp/multidrug resistance 1), encoded by the ATP-binding cassette B1 gene, is primarily involved in the transepithelial efflux of toxic metabolites and xenobiotics from the mucosa into the gut lumen. Reduced Pgp function and expression has been shown to be associated with i...

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Библиографические подробности
Главные авторы: Saksena, Seema, Priyamvada, Shubha, Kumar, Anoop, Akhtar, Maria, Soni, Vikas, Anbazhagan, Arivarasu Natarajan, Alakkam, Anas, Alrefai, Waddah A., Dudeja, Pradeep K., Gill, Ravinder K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2013
Предметы:
Mucosal Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602685/
https://ncbi.nlm.nih.gov/pubmed/23328208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00445.2012
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