Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells

Intestinal P-glycoprotein (Pgp/multidrug resistance 1), encoded by the ATP-binding cassette B1 gene, is primarily involved in the transepithelial efflux of toxic metabolites and xenobiotics from the mucosa into the gut lumen. Reduced Pgp function and expression has been shown to be associated with i...

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Main Authors: Saksena, Seema, Priyamvada, Shubha, Kumar, Anoop, Akhtar, Maria, Soni, Vikas, Anbazhagan, Arivarasu Natarajan, Alakkam, Anas, Alrefai, Waddah A., Dudeja, Pradeep K., Gill, Ravinder K.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2013
主題:
Mucosal Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602685/
https://ncbi.nlm.nih.gov/pubmed/23328208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00445.2012
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