Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells

Intestinal P-glycoprotein (Pgp/multidrug resistance 1), encoded by the ATP-binding cassette B1 gene, is primarily involved in the transepithelial efflux of toxic metabolites and xenobiotics from the mucosa into the gut lumen. Reduced Pgp function and expression has been shown to be associated with i...

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Autores principales: Saksena, Seema, Priyamvada, Shubha, Kumar, Anoop, Akhtar, Maria, Soni, Vikas, Anbazhagan, Arivarasu Natarajan, Alakkam, Anas, Alrefai, Waddah A., Dudeja, Pradeep K., Gill, Ravinder K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Mucosal Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602685/
https://ncbi.nlm.nih.gov/pubmed/23328208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00445.2012
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