Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells

Intestinal P-glycoprotein (Pgp/multidrug resistance 1), encoded by the ATP-binding cassette B1 gene, is primarily involved in the transepithelial efflux of toxic metabolites and xenobiotics from the mucosa into the gut lumen. Reduced Pgp function and expression has been shown to be associated with i...

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Detalhes bibliográficos
Main Authors: Saksena, Seema, Priyamvada, Shubha, Kumar, Anoop, Akhtar, Maria, Soni, Vikas, Anbazhagan, Arivarasu Natarajan, Alakkam, Anas, Alrefai, Waddah A., Dudeja, Pradeep K., Gill, Ravinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Mucosal Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3602685/
https://ncbi.nlm.nih.gov/pubmed/23328208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00445.2012
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