Colonic delivery of vasoactive intestinal peptide nanomedicine alleviates colitis and shows promise as an oral capsule

AIM: To evaluate the efficacy of locally delivered nanomedicine, vasoactive intestinal peptide in sterically stabilized micelles (VIP-SSM) to the colon and conduct in vitro release studies of a potential oral formulation. MATERIALS & METHODS: Intracolonic instillation of VIP-SSM was tested in a...

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Vydáno v:Nanomedicine (Lond)
Hlavní autoři: Jayawardena, Dulari, Anbazhagan, Arivarasu N, Priyamvada, Shubha, Kumar, Anoop, Saksena, Seema, Onyuksel, Hayat, Dudeja, Pradeep K
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Medicine Ltd 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7713900/
https://ncbi.nlm.nih.gov/pubmed/32975467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2020-0280
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