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How To Optimally Combine Genotypic and Phenotypic Drug Susceptibility Testing Methods for Pyrazinamide

False-susceptible phenotypic drug-susceptibility testing (DST) results for pyrazinamide due to mutations with MICs close to the critical concentration (CC) confound the classification of pncA resistance mutations, leading to an underestimate of the specificity of genotypic DST. This could be minimiz...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Köser, Claudio U., Cirillo, Daniela M., Miotto, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449218/
https://ncbi.nlm.nih.gov/pubmed/32571824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01003-20
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