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How To Optimally Combine Genotypic and Phenotypic Drug Susceptibility Testing Methods for Pyrazinamide

False-susceptible phenotypic drug-susceptibility testing (DST) results for pyrazinamide due to mutations with MICs close to the critical concentration (CC) confound the classification of pncA resistance mutations, leading to an underestimate of the specificity of genotypic DST. This could be minimiz...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Köser, Claudio U., Cirillo, Daniela M., Miotto, Paolo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449218/
https://ncbi.nlm.nih.gov/pubmed/32571824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01003-20
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