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Interspecies Differences in Tenofovir Alafenamide Fumarate Stability in Plasma

Tenofovir (TFV) alafenamide fumarate (TAF) is an antiretroviral that has been evaluated in alternative drug delivery systems in several species. The ex vivo stability of TAF was evaluated, and TAF was stable in dog-, sheep-, and macaque-spiked plasma. A negative bias was observed in TAF recovery in...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Parsons, Teresa L., Gwenden, Kevin N., Marzinke, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449208/
https://ncbi.nlm.nih.gov/pubmed/32540983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00930-20
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