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Tenofovir alafenamide versus tenofovir disoproxil fumarate: is there a true difference in efficacy and safety?

BACKGROUND: Higher plasma tenofovir concentrations are associated with higher risks of renal and bone adverse events. The pharmacokinetic boosters ritonavir (RTV) and cobicistat (COBI) significantly increase plasma area under the curve (AUC) concentrations of tenofovir disoproxil fumarate (TDF), by...

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Bibliografiske detaljer
Udgivet i:J Virus Erad
Main Authors: Hill, Andrew, Hughes, Sophie L, Gotham, Dzintars, Pozniak, Anton L
Format: Artigo
Sprog:Inglês
Udgivet: Mediscript Ltd 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892670/
https://ncbi.nlm.nih.gov/pubmed/29682298
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