Renal safety of tenofovir alafenamide vs. tenofovir disoproxil fumarate: a pooled analysis of 26 clinical trials

OBJECTIVE: Compared with tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF) has been associated with improvement in markers of renal dysfunction in individual randomized trials; however, the comparative incidence of clinically significant renal events remains unclear. DESIGN: We used a...

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Vydáno v:AIDS
Hlavní autoři: Gupta, Samir K., Post, Frank A., Arribas, José R., Eron, Joseph J., Wohl, David A., Clarke, Amanda E., Sax, Paul E., Stellbrink, Hans-Jürgen, Esser, Stefan, Pozniak, Anton L., Podzamczer, Daniel, Waters, Laura, Orkin, Chloe, Rockstroh, Jürgen K., Mudrikova, Tatiana, Negredo, Eugenia, Elion, Richard A., Guo, Susan, Zhong, Lijie, Carter, Christoph, Martin, Hal, Brainard, Diana, SenGupta, Devi, Das, Moupali
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2019
Témata:
Clinical Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635043/
https://ncbi.nlm.nih.gov/pubmed/30932951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002223
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