Plasma and Intracellular Pharmacokinetics of Tenofovir in Patients Switched from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide

OBJECTIVES: The aim of the study was to compare the intra-individual plasma and intracellular peripheral blood mononuclear cell (PBMC) pharmacokinetics (PK) of tenofovir (TFV) and its intracellular metabolite, tenofovir-diphosphate (TFV-DP) in patients switched from a fixed dose combination (FDC) ta...

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Vydáno v:AIDS
Hlavní autoři: PODANY, Anthony T., BARES, Sara H, HAVENS, Joshua, SHETTY, Ravi Dyavar, O’NEILL, Jennifer, LEE, Sarah, FLETCHER, Courtney V., SWINDELLS, Susan, SCARSI, Kimberly K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854526/
https://ncbi.nlm.nih.gov/pubmed/29334548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001744
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