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Interspecies Differences in Tenofovir Alafenamide Fumarate Stability in Plasma

Tenofovir (TFV) alafenamide fumarate (TAF) is an antiretroviral that has been evaluated in alternative drug delivery systems in several species. The ex vivo stability of TAF was evaluated, and TAF was stable in dog-, sheep-, and macaque-spiked plasma. A negative bias was observed in TAF recovery in...

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Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Parsons, Teresa L., Gwenden, Kevin N., Marzinke, Mark A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449208/
https://ncbi.nlm.nih.gov/pubmed/32540983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00930-20
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