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Interspecies Differences in Tenofovir Alafenamide Fumarate Stability in Plasma

Tenofovir (TFV) alafenamide fumarate (TAF) is an antiretroviral that has been evaluated in alternative drug delivery systems in several species. The ex vivo stability of TAF was evaluated, and TAF was stable in dog-, sheep-, and macaque-spiked plasma. A negative bias was observed in TAF recovery in...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Parsons, Teresa L., Gwenden, Kevin N., Marzinke, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449208/
https://ncbi.nlm.nih.gov/pubmed/32540983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00930-20
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