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Copper-Catalyzed C–H Fluorination/Functionalization Sequence Enabling Benzylic C–H Cross Coupling with Diverse Nucleophiles

Site-selective transformation of benzylic C–H bonds into diverse functional groups is achieved via Cu-catalyzed C–H fluorination with N-fluorobenzenesulfonimide (NFSI), followed by substitution of the resulting fluoride with various nucleophiles. The benzyl fluorides generated in these reactions are...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Vasilopoulos, Aristidis, Golden, Dung L., Buss, Joshua A., Stahl, Shannon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7446105/
https://ncbi.nlm.nih.gov/pubmed/32790420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c02238
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