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Site-Selective Copper-Catalyzed Azidation of Benzylic C─H Bonds

Site selectivity represents a key challenge for nondirected C─H functionalization, even when the C─H bond is intrinsically reactive. Here, we report a copper-catalyzed method for benzylic C─H azidation of diverse molecules. Experimental and density functional theory studies suggest the benzyl radica...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Suh, Sung-Eun, Chen, Si-Jie, Mandal, Mukunda, Guzei, Ilia A., Cramer, Christopher J., Stahl, Shannon S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405889/
https://ncbi.nlm.nih.gov/pubmed/32539355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05362
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