Wird geladen...
Structure-activity analysis of truncated albumin-binding domains suggests new lead constructs for potential therapeutic delivery
Rapid clearance by renal filtration is a major impediment to the translation of small bioactive biologics into drugs. To extend serum t(1/2), a commonly used approach is to attach drug leads to the G-related albumin-binding domain (ABD) to bind albumin and evade clearance. Despite the success of thi...
Gespeichert in:
| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2020
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443490/ https://ncbi.nlm.nih.gov/pubmed/32647013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014168 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|