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Effects of pharmacologically induced Leydig cell testosterone production on intratesticular testosterone and spermatogenesis(†)

The Leydig cells of the mammalian testis produce testosterone (T) in response to luteinizing hormone (LH). In rats and men with reduced serum T levels, T replacement therapy (TRT) will raise T levels, but typically with suppressive effects on sperm formation. The rate-determining step in T formation...

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Podrobná bibliografie
Vydáno v:Biol Reprod
Hlavní autoři: Chung, Jin-Yong, Brown, Sean, Chen, Haolin, Liu, June, Papadopoulos, Vassilios, Zirkin, Barry
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443349/
https://ncbi.nlm.nih.gov/pubmed/31504200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz174
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