Oxidative Stress and Phthalate-Induced Down-Regulation of Steroidogenesis in MA-10 Leydig Cells*

Previous studies have shown that phthalate exposure can suppress steroidogenesis. However, the affected components of the steroidogenic pathway, and the mechanisms involved, remain uncertain. We show that incubating MA-10 Leydig cells with mono-(2-ethylhexyl) phthalate (MEHP) resulted in reductions...

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Autori principali: Zhou, Liang, Beattie, Matthew C., Lin, Chieh-Yin, Liu, June, Traore, Kassim, Papadopoulos, Vassilios, Zirkin, Barry R., Chen, Haolin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836854/
https://ncbi.nlm.nih.gov/pubmed/23969005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2013.07.025
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