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Molecular Mechanisms Mediating the Effect of Mono-(2-Ethylhexyl) Phthalate on Hormone-Stimulated Steroidogenesis in MA-10 Mouse Tumor Leydig Cells

Di-(2-ethylhexyl) phthalate, a widely used plasticizer, and its active metabolite, mono-(2-ethylhexyl) phthalate (MEHP), have been shown to exert adverse effects on the reproductive tract in developing and adult animals. As yet, however, the molecular mechanisms by which they act are uncertain. In t...

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Autores principales: Fan, Jinjiang, Traore, Kassim, Li, Wenping, Amri, Hakima, Huang, Hongzhan, Wu, Cathy, Chen, Haolin, Zirkin, Barry, Papadopoulos, Vassilios
Formato: Artigo
Lenguaje:Inglês
Publicado: The Endocrine Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903930/
https://ncbi.nlm.nih.gov/pubmed/20463053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0010
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