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Steroidogenic Fate of the Leydig Cells that Repopulate the Testes of Young and Aged Brown Norway Rats after Elimination of the Preexisting Leydig Cells

The capacity of Brown Norway rat Leydig cells to produce testosterone (T) decreases with aging. In a previous study, we reported that a new generation of Leydig cells can be restored in both young and old rat testes after a single injection of ethane dimethanesulfonate (EDS), and that the abilities...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Chen, Haolin, Guo, Jingjing, Ge, Renshan, Lian, Qingquan, Papadopoulos, Vassilios, Zirkin, Barry R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654651/
https://ncbi.nlm.nih.gov/pubmed/26335619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2015.08.014
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