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Effects of pharmacologically induced Leydig cell testosterone production on intratesticular testosterone and spermatogenesis(†)

The Leydig cells of the mammalian testis produce testosterone (T) in response to luteinizing hormone (LH). In rats and men with reduced serum T levels, T replacement therapy (TRT) will raise T levels, but typically with suppressive effects on sperm formation. The rate-determining step in T formation...

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Publicado en:Biol Reprod
Autores principales: Chung, Jin-Yong, Brown, Sean, Chen, Haolin, Liu, June, Papadopoulos, Vassilios, Zirkin, Barry
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443349/
https://ncbi.nlm.nih.gov/pubmed/31504200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz174
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