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Effects of pharmacologically induced Leydig cell testosterone production on intratesticular testosterone and spermatogenesis(†)

The Leydig cells of the mammalian testis produce testosterone (T) in response to luteinizing hormone (LH). In rats and men with reduced serum T levels, T replacement therapy (TRT) will raise T levels, but typically with suppressive effects on sperm formation. The rate-determining step in T formation...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biol Reprod
Main Authors: Chung, Jin-Yong, Brown, Sean, Chen, Haolin, Liu, June, Papadopoulos, Vassilios, Zirkin, Barry
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443349/
https://ncbi.nlm.nih.gov/pubmed/31504200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz174
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