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Effects of pharmacologically induced Leydig cell testosterone production on intratesticular testosterone and spermatogenesis(†)

The Leydig cells of the mammalian testis produce testosterone (T) in response to luteinizing hormone (LH). In rats and men with reduced serum T levels, T replacement therapy (TRT) will raise T levels, but typically with suppressive effects on sperm formation. The rate-determining step in T formation...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Chung, Jin-Yong, Brown, Sean, Chen, Haolin, Liu, June, Papadopoulos, Vassilios, Zirkin, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443349/
https://ncbi.nlm.nih.gov/pubmed/31504200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz174
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