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Effects of pharmacologically induced Leydig cell testosterone production on intratesticular testosterone and spermatogenesis(†)
The Leydig cells of the mammalian testis produce testosterone (T) in response to luteinizing hormone (LH). In rats and men with reduced serum T levels, T replacement therapy (TRT) will raise T levels, but typically with suppressive effects on sperm formation. The rate-determining step in T formation...
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| Published in: | Biol Reprod |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7443349/ https://ncbi.nlm.nih.gov/pubmed/31504200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz174 |
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