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Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role. We adapted a CRISPR‐based proteomics approach to identify novel factors associated with var genes in their natural chro...

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Dades bibliogràfiques
Publicat a:Mol Syst Biol
Autors principals: Bryant, Jessica M, Baumgarten, Sebastian, Dingli, Florent, Loew, Damarys, Sinha, Ameya, Claës, Aurélie, Preiser, Peter R, Dedon, Peter C, Scherf, Artur
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440042/
https://ncbi.nlm.nih.gov/pubmed/32816370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20209569
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